Tag Archives: birdshot clinical research

ASTUTE – a new clinical trial starting

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We are pleased to tell you about a new clinical trial called ASTUTE which is due to start in England in 2021. BUS has been involved in helping plan this trial.   

ASTUTE will use an adalimumab biosimilar as the study medication. This will be added on to existing standard treatments for non-infectious autoimmune uveitis. Adalimumab biosimilars are newer, highly similar versions of the original adalimumab, Humira. 

The ASTUTE trial will be looking at how effective the study medication is, how well it is tolerated and how cost-effective it is. 

ASTUTE is designed to help doctors find out how the use of an adalimumab biosimilar might improve the treatment of a broad group of non-infectious autoimmune uveitis patients. The trial should also show which patients would benefit the most from adalimumab treatment.

Birdshot patients who do not currently meet the NICE criteria in England for adalimumab treatment may be considered for enrolment in the ASTUTE trial, as well as those who do.

To find out more about ASTUTE and to read the patient information leaflet, go to https://bristoltrialscentre.blogs.bristol.ac.uk/details-of-studies/astute/

Future newsletters will include updates on how the ASTUTE trial is progressing, and we will also let you know which hospital sites have opened for recruitment to the trial. 

July 2021

Small Grants Award Scheme for Birdshot Research

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We are delighted to announce that this year we have three awards available under the jointly funded small research projects scheme which Fight for Sight run.

Details about these awards are below:

Awards under this scheme are designed to provide support for birdshot clinical research studies only. The studies are to be conducted into any of the charity’s six research priority areas as detailed in the Charity’s Research Strategy 2012-2017. In addition the charity is keen to address the priorities identified by the Sight Loss and Vision Priority Setting Partnership

Fight for Sight is an NIHR Partner Organisation which means that clinical studies we fund are eligible for inclusion in the NIHR Clinical Research Network Portfolio. This allows the study team to have access to clinical infrastructure/NHS Service Support through the NIHR Clinical Research Networks.

Fight for Sight operates a Peer Review system that the charity believes enables an equitable and efficient way to review grant applications. Fight for Sight is unable to provide feedback for the Small Grant Awards Schemes.

Eligibility

  • Applicant must be affiliated with a UK academic or medical institutions.
  • Applicants must have a contract which extends beyond the termination date of the award.
  • These awards are limited to clinical research projects in the field of ophthalmology and vision science. Clinical research is research that either directly involves human participants or uses materials from patients (including human samples and human data).
  • These awards must not involve the use of animals or animal derived cell lines / samples.

Financial support and duration

  • Awards for up to £15,000.
  • Includes the costs of
    • employment (except Applicants; clinical applicants are expected to have protected research time in their NHS contracts);
    • consumables; and
    • equipment essential for the project.
  • Excludes indirect costs and any other non-attributable overhead costs.
  • These awards are tenable for up to 12 months.
  • These awards are not to be used to top-up existing grants.

Deadline

The call for “Small Grant Awards” is now open. The closing date for application submissions is 5pm on Wednesday 23 August 2017.

Application must be submitted via our online system grants.fightforsight.org.uk
Late applications will not be considered.