We came across this article on the BBC News website about the affect of Zinc on controlling the immune system and wondered if it has any relevance for Birdshotters? Continue reading
A paper entitled “Reappraisal of birdshot retinochoroiditis (BRC): a global approach.” has just been published by M Papdia and C P Herbort. Continue reading
Some of you may know that there have been trials on the drug, Sirolimus, which is given intravitreally or subconjunctivally (i.e. into the eye).
The idea behind this medication is that it should allow us to decrease our use of steroids which have such horrible side-effects, and it tends not to give so many other side effects, and it is not taken systemically (i.e. into our bodies). Continue reading
There has been an overwhelming number of papers being produced on helminthic therapy (worms) recently. This is exciting, as it means that it is a therapy that is being taken seriously, and therefore may well get to trial quite soon. Continue reading
I have already posted about the moves being made in gene therapy. Andrew Dick (who chairs the Birdshot Research Network) and colleagues have published a paper on gene therapy for non infectious uveitis, including severe forms of posterior uveitis such as Birdshot. Continue reading
Stephen Foster and associates have published a paper on Treatment of Birdshot with Infliximab. You may be aware that Stephen Foster is hosting the 2013 Birdshot Day on 28 September 2013, in Boston, United States. He has a profound interest in Birdshot and was instrumental in helping us set up BUS. Continue reading
The Shanghai Institutes for Biological Sciences has published a paper on Mesenchymal stem Cells (MSCs). The Institute believes that MSCs are emerging as a promising therapeutic approach of a cell-based therapy for a wide range of auto-immune disorders and degenerative diseases. Continue reading
We came across a fabulous article in the New Zealand Herald about work that Australian scientists, Tyani Chan and Robert Brink from Sydney’s Garvan Institute of Medical Research have undertaken. Continue reading
Qingkailing is a chinese medicine formula which has been used for cerebrovascular diseases and some inflammatory diseases including uveitis. At one stage, about five years ago, there was some work in the US looking at the possibilities of using this for uveitis. It is given as an injection and has a number of ingredients including some traditional roots and flowers.
There has been a recent trial at Shandong University of Traditional Medicine Eye Hospital where qingkailing was injected into rats with autoimmune uveitis (Birdshot is an autoimmune uveitis). It was found that it could offer immunomodulatory effects.
If this is the case (it will need to be trialled on people too), it could be a possible alternative to the rather toxic systemic medications we currently have to take.
Read the full story at
The Institute of Immunology and Infection Research at University of Edinburgh has published a paper on Helminth (worm) infections and host immune regulation. It looks at countries and areas where helminth parasites are endemic (i.e. many people carry these worms all their lives) and note that in these countries, there is a very low incidence of autoimmune diseases and allergies. This suggests that the helminth parasites may protect against your immune system becoming disregulated.
The paper points out that there is now much interest in investigating helminths as a therapy, in both laboratory models and in human trials. They believe that understanding and exploiting the way these parasites work are likely to highlight new strategies to control both infectious and immunological diseases.
See the full text at: